Pregnancy Outcome with Intrauterine Insemination in Patients with Unexplained Recurrent Abortion Whose Partners Have Abnormal Hypo-Osmotic Swelling Test

نویسندگان

  • Saeed Alborzi
  • Talie Kazerooni
  • Zohreh Tavana
چکیده مقاله:

Background: Recurrent abortion is defined as three or more consecutive pregnancy losses. We aimed to determine the relationship between male sperm parameters and hypo-osmotic swelling score and recurrent abortion. We also studied whether washing of spermatozoa and intrauterine insemination in patients with recurrent miscarriage and low score hypo-osmotic swelling test in male partners could improve the outcome of pregnancy. Methods: Between February 2003 and September 2006 in gynecology clinics affiliated to Shiraz University of Medical Sciences, 176 women with a history of recurrent abortion and their male partners were selected as study group. And 159 healthy and fertile couples without a history of recurrent abortion were selected as control group. The relationship between male sperm parameters and hypo-osmotic swelling test and recurrent spontaneous abortion in their female partners was evaluated after intrauterine insemination for those with abnormal hypo-osmotic swelling test. Outcome of pregnancy in patients with recurrent abortion whose male partners had low score hypo-osmotic swelling test was evaluated after intrauterine insemination. Results: Low scores of hypo-osmotic swelling test were more frequently seen in the study group than the controls: 116 (65%) versus 24 (15%). The mean hypo-osmotic swelling score was significantly lower in the study group (P< 0.001). The outcome of pregnancy improved after intrauterine insemination in those with low score hypo-osmotic swelling test. The pregnancy success rate in the treated group (pregnant with intrauterine insemination) was 77.77% while in the untreated group (pregnant without intrauterine insemination) was 30.76% with a success rate ratio of 2.04. Conclusion: There was a positive relationship between low hypo-osmotic swelling test score in male partners and recurrent abortion in their wives. Intrauterine insemination improved the outcome of pregnancy in these couples.

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منابع مشابه

pregnancy outcome with intrauterine insemination in patients with unexplained recurrent abortion whose partners have abnormal hypo-osmotic swelling test

background: recurrent abortion is defined as three or more consecutive pregnancy losses. we aimed to determine the relationship between male sperm parameters and hypo-osmotic swelling score and recurrent abortion. we also studied whether washing of spermatozoa and intrauterine insemination in patients with recurrent miscarriage and low score hypo-osmotic swelling test in male partners could imp...

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SUCCESSFUL PREGNANCY OUTCOME WITH lUI IN PATIENTS WITH UNEXPLAINED RECURRENT MISCARRIAGE, WHOSE MALE PARTNERS HAVE LOW SCORE HYPO-OSMOTIC SWELLING TEST

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successful pregnancy outcome with lui in patients with unexplained recurrent miscarriage, whose male partners have low score hypo-osmotic swelling test

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The role of hypo-osmotic swelling test in recurrent abortions.

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عنوان ژورنال

دوره 34  شماره 3

صفحات  172- 176

تاریخ انتشار 2009-09-01

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